XPL7 is a vaginal suppository that comes in an applicator. When it is used within 72 hours (3 Days) after an unprotected sexual exposure it can prevent pregnancy.

Proposed Mechanism of action: There are a group of fatty acid derivatives called Prostaglandins that are produced in most tissues of the body and have varying physiologic actions.

Sune Bergstrom a swedish scientist won the Nobel Prize in 1982 for his work on Prostaglandins. To read one of his articles Click Here. See pages 10-12.   ( Acrobat reader required.)

Prostaglandins act in a manner similar to that of hormones, by stimulating target cells into action. However, they differ from hormones in that they act locally, near their site of synthesis, and they are metabolized very rapidly. Another unusual feature is that the same prostaglandins act differently in different tissues. The effects of Prostaglandins on the reproductive process have been well documented.

Prostaglandins have diverse actions dependent on cell type but are known to generally cause smooth muscle contraction. The vasoconstrictive and muscle constricting activities of prostaglandins contribute to the normal sloughing of the endometrial lining during menstruation. The fatty acids in the herbal formulation are synthesised into Prostaglandins which may trigger and or accelerate this process.

The herbal formulation contained in XPL7 contains some fatty acids that are converted into Prostaglandins by the body tissue and can produce their effects on a cell level in the endothelium.

To find out more about the increasing worldwide acceptance of Emergency Contraception please check out this Newsletter.